Optimization of Prostate Biopsy

Optimization of Prostate Biopsy Referral Decisions

Prostate cancer is the most common solid tumor in American men and is screened for using prostate-specific antigen (PSA) tests. We report on a non-stationary partially observable Markov decision process (POMDP) for prostate biopsy referral decisions. The core states are the patients’ prostate cancer related health states, and PSA test results are the observations. Transition probabilities and r...

Stereotactic transperineal prostate biopsy.

This study investigates the detection rate of nonpalpable, isoechoic occult prostate malignancy using a stereotactic transperineal prostate biopsy (STPB) technique in patients with a previously negative transrectal ultrasound-guided prostate biopsy.

Geometric systematic prostate biopsy.

OBJECTIVE The common sextant prostate biopsy schema lacks a three-dimensional (3D) geometric definition. The study objective was to determine the influence of the geometric distribution of the cores on the detection probability of prostate cancer (PCa). METHODS The detection probability of significant (>0.5 cm3) and insignificant (<0.2 cm3) tumors was quantified based on a novel 3D capsule mo...

Optimizing prostate biopsy techniques.

W hat is the optimal biopsy strategy for detecting clinically important prostate carcinoma? I am not sure we are any closer in 2007 than we were in 1989 when the 6-core biopsy technique became the standard of care. Take too few cores and clinically significant cancers might be missed. However, take too many cores and clinically indolent cancer may be identified. Data from the early 1990s demons...

analgesia for prostate biopsy: efficacy of diclofenac patch versus diclofenac suppository as compared to placebo during prostate biopsy